You ask the questions - we develop the answers.

We combine professional management with scientific expertise.

The Institute for Pharmacology and Preventive Medicine

The Institute is an experienced partner of universities, non-university institutions, health insurance companies, and pharmaceutical companies in the implementation of scientific projects in the fields of cardiovascular disease and diabetes.

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We offer the trustworthy advice of a medical doctor and a pharmacist.

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Clinical Registries

Clinical registries across Europe are our primary area of expertise.

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Validation Centre

We will test and validate your blood pressure monitors.

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IPPMed Partnership

Prof. Dr. Peter Bramlage (physician) and Dr. Johannes Hankowitz (pharmacist) work closely together in the Institute for Pharmacology and Preventive Medicine, Dr. Bramlage & Dr. Hankowitz Partnership. Dr Bramlage focuses on collaboration with partners from industry and universities on scientific questions and the evaluation and publication of study data. Dr Hankowitz is experienced in the preparation and assessment of drug evaluations within the AMNOG (Pharmaceuticals Market Reorganisation Act) and editor of AMNOG-monitor.


Our activities in the areas of clinical registries and validation of blood pressure monitoring devices are a part of IPPMed – Institute for Pharmacology and Preventive Medicine GmbH. This is managed by Prof. Dr. Peter Bramlage and Beate Beime. Here, together with the highly experienced staff at our office in Cloppenburg, we regularly carry out large scale projects involving the latest pharmaceuticals and medical devices.
The close collaboration with clients, as well as with external investigators, ensures the high quality of our work. We focus primarily on cardiovascular indications, hypertension, thrombosis, and diabetes.

Scientist / Physician wanted!
Medical Writer wanted!

To enhance our scientific output we are looking for an experienced scientist with cardiovascular disease experience as well as a (native English) Medical Writer.

Recent Activity / Publications in press

Tzamalis P, Herzberger V, Bergmann J, Wuerth A, Bramlage P, Schroefel H, Schmitt C, Schymik G. The association of diabetes mellitus treated with oral antidiabetic drugs and insulin with mortality after transcatheter valve implantation – A three-year follow-up of the TAVIK registry. Cardiovasc Diabetol 2019.

Pfohl M, Pscherer S, Fritsche A, Anderten H, Borck A, Pegelow K, Bramlage P, Seufert J. Predictors of treatment response in type-2 diabetes patients initiating basal-supported oral therapy with insulin glargine 100 U/mL – a sub-analysis of the Titration and OPtimisation (TOP) registry. Diab Metab Obes 2019.

van Mark G, Lanzinger S, Sziegoleit S, Putz FJ, Durmaz M, Borscheller M, Danne T, Seufert J, Holl RW, Bramlage P.Characteristics of patients with type 1 or type 2 diabetes receiving insulin glargine U300 – an analysis of 7,268 patients based on the DPV and DIVE registries. Adv Ther 2019.

Hundertmark M, Williams T, Vogel A, Moritz M, Bramlage P, Pagonas N, Ritter O, Sasko B. Capnocytophaga canimorsus as cause of fatal sepsis. Case Rep Infect Dis 2019.

Frank D, Kennon S, Bonaros N, Romano M, Lefèvere T, Di Mario C, Stefàno P, Ribichini F, Himbert D, Urena-Alcazar M, Salgado-Fernandez J, Cuenca Castillo JJ, Garcia B, Kurucova J, Thoenes M, Lüske CM, Bramlage P, Styra R. A trial protocol for the validation of the “Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire” in patients undergoing Surgical Aortic Valve Replacement (SAVR) or Transfemoral (TF) Transcatheter Aortic Valve Implantation (TAVI) – The TASQ Registry. Open Heart 2019.

Cetinkaya A, Borsche A, Hein S, Bramlage P, Schönburg M, Richter M.Explantation and reimplantation of a breast implant to facilitate minimally invasive mitral valve surgery (MIMVS) and cryoablation of atrial fibrillation. Clin Case Rep 2019.

Nielsen NE, Baranowska J, Bramlage P, Baranowski J. Minimising the risk for left ventricular rupture during transcatheter aortic valve implantation by reducing stiff guidewires presence in the ventricle. ICVTS 2019.

Baumbach H, Schairer ER, Wachter K, Rustenbach C, Ahad S, Stan A, Hill S, Bramlage P, Franke UW, Schäufele T. Transcatheter aortic valve replacement- management of patients with significant coronary artery disease undergoing aortic valve interventions: surgical compared to catheter-based approaches in hybrid procedures. BMC Cardiovasc Disord 2019.

Schmieder RE, Högerl K, Jung S, Bramlage P, Veelken R, Ott C. Patient preference for therapies in hypertension: a cross-sectional survey of German patients. Clin Res Cardiol 2019.

Bramlage P, Lanzinger S, van Mark G, Hess E, Fahrner S, Heyer CHJ, Friebe M, Seufert J, Danne T, Holl RW. Patient and disease characteristics of type-2 diabetes patients with or without chronic kidney disease – an analysis of the German DPV and DIVE databases. Cardiovascular Diabetology 2019.

PubMed listed Publications

Our Partners

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