You ask the questions - we develop the answers.

We combine professional management with scientific expertise.

The Institute for Pharmacology and Preventive Medicine

The Institute is an experienced partner of universities, non-university institutions, health insurance companies, and pharmaceutical companies in the implementation of scientific projects in the fields of cardiovascular disease and diabetes.

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Registries / Studies

Registries and studies across Europe are our expertise.

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Validation Centre

We validate the accuracy of your blood pressure monitors.

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Trustworthy advice of a medical doctor and a pharmacist.

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IPPMed Partnership

Prof. Dr. Peter Bramlage (physician) and Dr. Johannes Hankowitz (pharmacist) work closely together in the Institute for Pharmacology and Preventive Medicine, Dr. Bramlage & Dr. Hankowitz Partnership. Dr Bramlage focuses on collaboration with partners from industry and universities on scientific questions and the evaluation and publication of study data. Dr Hankowitz is experienced in the preparation and assessment of drug evaluations within the AMNOG (Pharmaceuticals Market Reorganisation Act) and editor of AMNOG-monitor.


Our activities in the areas of clinical registries and validation of blood pressure monitoring devices are a part of IPPMed – Institute for Pharmacology and Preventive Medicine GmbH. This is managed by Prof. Dr. Peter Bramlage and Beate Beime. Here, together with the highly experienced staff at our office in Cloppenburg, we regularly carry out large scale projects involving the latest pharmaceuticals and medical devices.
The close collaboration with clients, as well as with external investigators, ensures the high quality of our work. We focus primarily on cardiovascular indications, hypertension, thrombosis, and diabetes.

Project Manager wanted!

We are looking for a project manager in the field of registries / studies for our office located in Cloppenburg.

Recent Activity / Publications in press

Geller JC, Wöhrle A, Busch M, Elsässer A, Kleemann T, Birkenhauer F, Bramlage P, Veltmann C for the ReduceIT Investigators. Reduction of Inappropriate Implantable Cardioverter-Defibrillator Therapies using Enhanced Supraventricular Tachycardia Discriminators: the ReduceIT Study. JICE 2020.

Eltchaninoff E, Bonaros N, Prendergast B, Nietlispach F, Vasa-Nicotera M, Chieffo A, Pibarot P, Bramlage P, Sykorova L, Kurucova J, Bax JJ, Windecker S, Dumonteil N, Tchetche D. Rationale and design of a prospective, randomized, controlled, multicenter study to evaluate the safety and efficacy of transcatheter heart valve replacement in female patients with severe symptomatic aortic stenosis requiring aortic valve intervention (RHEIA trial). Am Heart J 2020.

Droppa M, Rudolph TK, Baan J, Nielsen NE, Baumgartner H, Vendrik J, Froehlich M, Borst O, Wöhrle J, Gawaz M, Potratz P, Hack LP, Mauri V, Baranowski J, Bramlage P, Kurucova J, Thoenes M, Rottbauer W, Geisler T. Risk Factors for Permanent Pacemaker Implantation in Patients Receiving a Balloon-Expandable Transcatheter Aortic Valve Prosthesis. Heart & Vessels 2020.

Bramlage P, Tittel SR, Wagner C, König K, Raddatz D, Weber-Lauffer R, Erath D, Hilgenberg J, Spies C, Danne T, Gabler M, Foersch J, Ley L, Seufert J. The DIVE / DPV registries: Evolution of empagliflozin use in clinical practice in Germany. BMJ Open Diabetes Research Care 2020.

Spence MS, Baan J, Iacovelli F, Martinelli GL, Muir DF, Saia F, Bortone AS, Densem CG, Owens CG, van der Kley F, Vis, M, van Mourik MS, Costa G, Sykorova L, Lüske CM, Deutsch C, Kurucova J, Thoenes M, Bramlage P, Tamburino C, Barbanti M. Pre-specified risk criteria facilitate adequate discharge and long-term outcomes after transfemoral TAVI. JAHA 2020

Rudolph TK, Messika-Zeitoun D, Frey N, Thambyrajah J, Serra A, Schulz E, Maly J, Aiello M, Lloyd G, Bortone AS, Clerici A, Delle-Karth G, Rieber J, Indolfi C, Mancone M, Belle L, Lauten A, Arnold M, Bouma BJ, Lutz M, Deutsch C, Kurucova J, Thoenes M, Bramlage P, Steeds RP. Impact of selected comorbidities on the presentation and management of aortic stenosis. Open Heart 2020.

Sandig D, Hermann J, Reinauer C, Melmer A, Zimny S, Müller-Korbsch M, Forestier N, Zeyfang A, Bramlage P, Danne T, Meissner T, Holl RW. Continuous glucose monitoring in adults with type 1 diabetes: Real-World Data from the German/Austrian DPV Registry. Diabetes Technology and Therapeutics 2020.

Meuris B, Borger MA, Bourguignon T, Siepe M, Grabenwöger M, Laufer G, Binder K, Polvani G, Stefano P, Coscioni E, van Leeuwen W, Demers P, Dagenais F, Canovas S, Theron A, Langanay T, Roussel JC, Wendler O, Mariscalco G, Pessotto R, Botta B, Bramlage P, de Paulis R. Durability of bioprosthetic aortic valves in patients under the age of 60 years – rationale and design of the international INDURE registry. Journal of Cardiothoracic Surgery 2020.

Caponcello MG, Banderas LM, Ferrero C, Bramlage C, Thoenes M, Bramlage P. Gender differences in AVR: Is SAVR more risky and TAVR safer in women than in men? J Thorac Dis 2020.

Studencan M, Pella D, Bramlage P, Kaszasova E. Clinical characteristics and management of hyperlipoproteinemia in patients with chronic coronary heart disease in Slovakia. Archives of Medical Science 2020

Previous publications

PubMed listed Publications

Our Partners

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