You ask the questions - we develop the answers.

We combine professional management with scientific expertise.

The Institute for Pharmacology and Preventive Medicine

The Institute is an experienced partner of universities, non-university institutions, health insurance companies, and pharmaceutical companies in the implementation of scientific projects in the fields of cardiovascular disease and diabetes.

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We offer the trustworthy advice of a medical doctor and a pharmacist.

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Clinical Registries

Clinical registries across Europe are our primary area of expertise.

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Validation Centre

We will test and validate your blood pressure monitors.

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IPPMed Partnership

Prof. Dr. Peter Bramlage (physician) and Dr. Johannes Hankowitz (pharmacist) work closely together in the Institute for Pharmacology and Preventive Medicine, Dr. Bramlage & Dr. Hankowitz Partnership. Dr Bramlage focuses on collaboration with partners from industry and universities on scientific questions and the evaluation and publication of study data. Dr Hankowitz is experienced in the preparation and assessment of drug evaluations within the AMNOG (Pharmaceuticals Market Reorganisation Act) and editor of AMNOG-monitor.


Our activities in the areas of clinical registries and validation of blood pressure monitoring devices are a part of IPPMed – Institute for Pharmacology and Preventive Medicine GmbH. This is managed by Prof. Dr. Peter Bramlage and Beate Beime. Here, together with the highly experienced staff at our office in Cloppenburg, we regularly carry out large scale projects involving the latest pharmaceuticals and medical devices.
The close collaboration with clients, as well as with external investigators, ensures the high quality of our work. We focus primarily on cardiovascular indications, hypertension, thrombosis, and diabetes.

Scientist / Physician wanted!
Medical Writer wanted!

To enhance our scientific output we are looking for an experienced scientist with cardiovascular disease experience as well as a (native English) Medical Writer.

Recent Activity / Publications in press

Hengstenberg C, Thoenes M, Bramlage P, Siller-Matula-J, Mascherbauer J. Aortic valve stenosis awareness in Austria – Results from a nationwide survey in 1001 subjects. Wiener Med Wochenschr 2019.

Pscherer S, Anderten H, Pfohl M, Fritsche A, Borck A, Pegelow K, Bramlage P, Seufert J. Titration of insulin glargine 100 U/mL when added to oral antidiabetic drugs in patients with type 2 diabetes – results of the TOP-1 real-world study. Acta Diabetologia 2019.

Fritsche A, Anderten H, Pfohl M, Pscherer S, Borck A, Pegelow K, Bramlage P, Seufert J. HbA1c target achievement in the elderly – results of the Titration and Optimization Trial for Initiation of Insulin Glargine 100 U/mL in Patients with Type 2 Diabetes Poorly Controlled on Oral Antidiabetic Drugs. BMJ Open Diabetes & Research 2019.

Rudolph TK, Messika-Zeitoun D, Frey N, Lutz M, Krapf L, Passefort S, Fryearson J, Simpson H, Mortensen K, Rehse S, Tiroke A, Dodos F, Mies F, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Steeds RP, for the IMPULSE enhanced investigators. Caseload management and outcome of patients with aortic stenosis in primary / secondary vs. tertiary care settings – design of the IMPULSE enhanced registry. Open Heart 2019.

van Mourik MS, van der Velde N, Mannarino G, Thibodeau MP, Masson JB, Santoro G, Baan J, Jansen S, Kurucova J, Thoenes M, Deutsch C, Schoenenberger AW, Ungar A, Bramlage P, Vis MM. Value of a Comprehensive Geriatric Assessment (CGA) for predicting 1-year outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) – results from the CGA-TAVI multicentre registry. J Geriatr Cardiol 2019.

Frey N, Steeds RP, Rudolph TK, Thambyrajah J, Serra A, Schulz E, Maly J, Aiello M, Lloyd G, Bortone AS, Hauptmann KE, Clerici A, Delle Karth G, Rieber J, Indolfi C, Mancone M, Belle L, Lauten A, Arnold M, Bouma BJ, Lutz M, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Messika-Zeitoun D for the IMPULSE registry group. Symptoms, disease severity, and treatment of adults with a new diagnosis of severe aortic stenosis. Heart 2019.

Baumbach H, Schairer E, Wachter K, Rustenbach C, Ahad S, Stan A, Hill S, Bramlage P, Franke UFW, Schäufele T. Transcatheter aortic valve replacement- management of patients with significant coronary artery disease undergoing aortic valve interventions: surgical compared to catheter-based approaches in hybrid procedures. BMC Cardiovasc Disorders 2019.

Cetinkaya A, Poggenpohl J, Bramlage K, Hein S, Doss M, Bramlage P, Schönburg M, Richter M. Long-term outcome after mitral valve replacement using biological versus mechanical valves. J Cardiothoracic Surgergy 2019;14(1):120.

Hundertmark M, Williams T, Vogel A, Moritz M, Bramlage P, Pagonas N, Ritter O, Sasko B. Capnocytophaga canimorsus as cause of fatal sepsis. Case Rep Infect Dis 2019.

Frank D, Kennon S, Bonaros N, Romano M, Lefèvere T, Di Mario C, Stefàno P, Ribichini F, Himbert D, Urena-Alcazar M, Salgado-Fernandez J, Cuenca Castillo JJ, Garcia B, Kurucova J, Thoenes M, Lüske CM, Bramlage P, Styra R. A trial protocol for the validation of the “Toronto Aortic Stenosis Quality of Life (TASQ) Questionnaire” in patients undergoing Surgical Aortic Valve Replacement (SAVR) or Transfemoral (TF) Transcatheter Aortic Valve Implantation (TAVI) – The TASQ Registry. Open Heart 2019.

PubMed listed Publications

Our Partners

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